What’s the difference between liposomes and DIVERSA’s nanoparticles?

Liposomes and nanoparticles are used in gene delivery, but they differ in structure and properties. 

Liposomes are spherical vesicles composed of one or more phospholipid bilayers surrounding an aqueous core. They are biocompatible and can associate with various polynucleotides, including RNA, typically upon the addition of a cationic lipid to their composition. 

In contrast, DIVERSA’s nanoparticles possess a more organized structure and incorporate key components for efficient encapsulation without relying on cationic lipids. They are designed to optimize intracellular delivery and endosomal escape while minimizing harm to cell membranes. Additionally, DIVERSA’s nanoparticles are patented, signifying a layer of innovation and facilitating clinical translation. 

DIVERSA also offers co-development services  to help you further advance your research project.