PRODUCT

DIVERSA Small Molecule Delivery Nanoparticles

Technical information

Drug	MW (g/mol)	log P_OW	Mass (mg)	% Loading (w/w)	Molar (mM)	% EE
Galunisertib	369.42	2.4	0.75	15%	2.03	>80%
Doramapimod	527.66	5.7	0.75	15%	1.42	>99%
Disulfiram	296.54	3.9	0.75	15%	2.53	>90%
Paclitaxel	853.91	2.5	0.05	1%	0.06	>80%
Etoposide	588.56	0.6	0.05	1%	0.09	>80%
Doxorubicin	543.52	1.3	1	20%	1.84	>90%
Oleuropein	540.51	-0.4	0.75	15%	1.39	>99%
Rose Bengal	973.67	8.5	1	20%	1.03	>95%

*MW: molecular weight, Log Pow: n-octanol/water partition coefficient, EE: encapsulation efficiency

Reference number

DIV010

Reagent

DIVERSA Small Molecule Delivery Reagent

Amount of reagent

4 x 1 mL

Molecules delivered

Small molecules

Cell types

Adherent & suspension cells, organoids and 3D cultures

Cell culture conditions

Cell culture medium supplemented with/without serum

Number of experiments

1 mL of DIVTECH Small molecule is sufficient to perform 27 delivery experiments in 6-well plates, 134 experiments in 24-well plates and 800 experiments in 96-well plates.

In vivo models

Rodents and zebrafish

Administration route

Intravenous, subcutaneous, intraperitoneal, intra-articular, topical…

Shipping

Room temperature

Storage

-20 ºC upon arrival, once formulated at 4 ºC

Provided with

4x DIVTECH empty vials, 8 tips for 1 mL pipette