Melanoma, a type of skin cancer originating from melanocytes, has become a global health concern due to its rising incidence. It ranks as the fifth most prevalent cancer in men and the sixth most common in women [1]. To advance in the fight against this [...]
2024 is here full of new resolutions and challenges. And so, in an ever-evolving field such as medicine, it's inevitable to wonder what exciting advances the new year will bring. Nature medicine has asked leading researchers to discover what clinical trials may impact medicine in [...]
The versatility of nanotechnology to fight different diseases in diverse therapeutic areas is unprecedented. Combining nanoparticles and mRNA to treat autoimmune diseases could be the latest blockbuster, adding the development of COVID-19 vaccines and the new announcement of promising results for a personalized mRNA vaccine [...]
Is it possible for a drug to go through a clinical trial more than once? Potent drugs with high therapeutic efficacy, such as the anticancer drug doxorubicin, generate adverse effects that reduce their application in clinical practice, limiting healthcare professionals' and patients' choices. Nanotechnology holds [...]
The Food and Drug Administration (FDA) has joined the UK medicines regulator and has approved the first CRISPR-Cas9 gene-editing therapy to treat sickle-cell disease [1]. UK expands approval to β-thalassemia. The approval of Casgevy, the therapy developed by Vertex and CRISPR Therapeutics, is the first [...]
Nanotechnology, the science of manipulating matter at the nanoscale level, has made leaps and bounds in recent years, revolutionizing industries and profoundly impacting our daily lives. The nanoscale is the start of everything; life was born at this atomic level. Biomolecules and their interactions, the [...]
RNA-based drugs are here to revolutionize the way we know pharmacology. Covid vaccines were just the tip of the iceberg, but much more awaits in the wings. A small interfering ribonucleic acid (siRNA)-based drug to treat hypercholesterolemia has been on the front pages these past [...]
The ability of microRNAs (miRNAs) to regulate gene expression in diverse biological processes provides new and potentially powerful candidates for therapeutic intervention. But, to date, no miRNAs have been approved for clinical treatment. What’s blocking the road from bench to bedside? Their transition into the [...]
Applications of lipid nanoparticles (LNPs) are limited by their accumulation in the liver. The absence of a targeted delivery plan of action usually leads to the hepatic tissue. How can we deliver LNPs loaded with therapeutic molecules to specific tissues and organs? Wang et al. [...]
No doubt, nanotechnology can boost the therapeutic efficiency of drug delivery. Nanodrugs, the combination of nanotechnology as the lipid nanoemulsions developed by DIVERSA, and pharmaceuticals, are a current hotspot in the medical field. Yet, once introduced into the human body, new players emerge. In the [...]
