Laura’s research in brief
Laura Taina-González, who is PhD candidate at DIVERSA, presented her ongoing research at SPLC-CRS Young Scientists Meeting last month. Her work is focused on optimizing DIVERSA’s delivery technology for the association of mRNA.
This line of research is motivated by the fast growth of mRNA technology, especially relying on Lipid Nanoparticles (LNPs), offering opportunities for innovative and critical applications.
At her poster and oral presentation, Laura explained the modification of sphingomyelin/vitamin E nanoemulsions with cationic and helper lipids. She also gave insight into the optimization of the composition by exploring the potential of different types of sphingomyelins and the incorporation of specific features of LNPs. She has also optimized the preparation methodology, obtaining mRNA-loaded lipid nanosystems quickly and reproducibly without using specific equipment.
After months of intense work characterizing all the formulations, she provided the first evidence regarding optimizing DIVERSA’s technology for mRNA delivery applications in vitro. The formulations showed a high association and transfection efficiencies in diverse cell lines.
Hard work pays off, and SLPC-CRS knows how to recognize it
Laura was awarded the best oral and poster communication for this work at the 4th SPLC-CRS Young Scientists Meeting in Porto last February.
The Controlled Release Society (CRS) is an international organization home to experts dedicated to delivery science, including 3.000 members from more than 50 countries.
CRS members are creating the future of delivery science and technology through fundamental delivery research, development, regulatory science, and clinical translation.
Participating in these Local Chapters allows for sharing results and experiences with different professionals — two days of fruitful conversations and dissemination of DIVERSA’s advances and points of view.
As you can see, we always enjoy participating in these events, which positively impact our researchers’ development.
Congratulations to Laura on the prizes! We are sure these are the first of many more to come. Keep up your hard work!
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