Search by category

Enhancing intracellular delivery of a broad range of peptides

DIVTECH Peptide Kit, based on reactive lipids, is suitable for click chemistry to conjugate any azide-modified peptide. N3-peptides will covalently react with the surface of the DIVTECH formulation by following easy and mild conditions. The modification in your peptide/s of interest is meant to facilitate its association to DIVTECH formulation and does not compromise its structure and activity.

ORDER AT TEBU-BIO
PROTOCOL
Technical information
Peptide delivered pl Peptide charge % hydrophobic Aa
3-mer
5.9
-1
0%
12-mer
9.5
+4
25%
13-mer
9.8
+5
23%
16-mer
9.5
+7
50%
19-mer
8.6
+2
21%
28-mer
11.9
+6
39%
Examples of peptides efficiently associated with DIVTECH and delivered to cells.

Reference number

DIV021

Reagent

DIVTECH Peptide Kit

Amount of reagent

2 x 1 mL

Molecules delivered

N3-modified peptides

Cell types

Adherent & suspension cells, organoids and 3D cultures

Cell culture conditions

Cell culture medium supplemented with/without serum

Number of experiments

1 mL of DIVTECH Small molecule is sufficient to perform 13 delivery experiments in 6-well plates, 68 experiments in 24-well plates and 405 experiments in 96-well plates.

In vivo models

Rodents and zebrafish

Administration route

Intravenous, subcutaneous, intraperitoneal, intra-articular, topical…

Storage

-20 ºC upon arrival, once formulated at 4 ºC

Provided with

2x DIVTECH empty vials, 4 tips for 1 mL pipette
DIV021
Size of DIVTECH-PEPTIDE formulations and stability after 24 hours in storage conditions.
DIV021
Colloidal stability of DIVTECH-PEPTIDE (12-mer and 19-mer peptides) formulations after 28 days in storage conditions.
DIV021
Therapeutic efficiency of intracellular delivered peptides in free form or with DIVTECH, and compared to commercial competitors.
DIV021
Intracellular delivery of FITC-labeled peptides to fibroblast in free form and using DIVTECH (blue: cell nuclei, red: cytoskeleton, green: DIVTECH-PEPTIDE).

Related products