Enhancing intracellular delivery of small molecules
DIVTECH Small Molecule kit is suitable for hydrophilic and hydrophobic small molecules and can be used to efficiently deliver your compound/drug of interest to specific cell lines. DIVTECH prevents loaded drugs from external degradation and rapid clearance. It promotes optimal and targeted biodistribution, high intracellular absorption and low toxicity, boosting their therapeutic effect.
Technical information
Drug | MW (g/mol) | log POW | Mass (mg) | % Loading (w/w) | Molar (mM) | % EE |
---|---|---|---|---|---|---|
Galunisertib |
369.42 |
2.4 |
0.75 |
15% |
2.03 |
>80% |
Doramapimod |
527.66 |
5.7 |
0.75 |
15% |
1.42 |
>99% |
Disulfiram |
296.54 |
3.9 |
0.75 |
15% |
2.53 |
>90% |
Paclitaxel |
853.91 |
2.5 |
0.05 |
1% |
0.06 |
>80% |
Etoposide |
588.56 |
0.6 |
0.05 |
1% |
0.09 |
>80% |
Doxorubicin |
543.52 |
1.3 |
1 |
20% |
1.84 |
>90% |
Oleuropein |
540.51 |
-0.4 |
0.75 |
15% |
1.39 |
>99% |
Rose Bengal |
973.67 |
8.5 |
1 |
20% |
1.03 |
>95% |